Mix tomatoes and tomato paste in slow cooker until well blended. Stir in vegetables and add Italian seasoning.
Cut mean into 8 pieces. Add to slow cooker; cover with lid. Cook low 4 to 4 1/2 hours.
Cook pasta as directed on package, omitting salt. When meat is cooked, transfer to plate reserving sauce in slow cooker. Cover meat to keep warm. Mix cornstarch and water until well blended. Add to sauce; stir. Cover an cook for 6-8 minutes.
Drain pasta; spoon onto plate. Top with meat, sauce and cheese.